Metal Cations In G-Quadruplex Folding And Stability
G-quadruplexes (G4s) are unique secondary structures of nucleic acids, particularly DNA and RNA, characterized by the stacking of planar arrangements of four guanine bases, stabilized by monovalent cations such as potassium (K?) or sodium (Na?). These structures play crucial roles in various biological processes, including gene regulation, telomere maintenance, and potentially in therapeutic applications against … Read more